oddityworld

Cancer Stem Cell Therapy Leaves Two Australian Patients HIV-FREE

The HIV/AIDS research treatment and patients took a huge blow when 100 HIV researchers, doctors, and advocates died on the Malaysia Airlines...


The HIV/AIDS research treatment and patients took a huge blow when 100 HIV researchers, doctors, and advocates died on the Malaysia Airlines Flight MH17 who were headed to their HIV/AIDS convention.

Their plane was shot down in Ukraine. But the hope in preventing the spread of the disease and to find the cure for deadly virus is still alive. One good news would be the recent development of the two Australian cancer patients’s HIV suddenly became undetectable (HIV-FREE) after they have received a bone-marrow therapy with stem cell treatment.

It is indeed a very good news to the HIV/AIDS community.

For precautionary reasons, The two patients will still undergo antiretroviral therapy. According to David Cooper, director of the Kirby Institute at the University of New South Wales in Sydney, the retroviral drugs alone could not be the reason for lowering the virus levels of the two patients and the stem cell treatment played a huge role for the said result.


According to Nature Journal :
Cooper began searching for patients who had been purged of the HIV virus after attending a presentation by a US team last year at a conference of the International AIDS Society in Kuala Lumpur. At that meeting, researchers from Brigham and Women’s Hospital in Boston, Massachusetts, reported that two patients who had received stem-cell transplants were virus-free.

Cooper and his collaborators scanned the archives of St Vincent’s hospital in Sydney, one of the largest bone-marrow centres in Australia. “We went back and looked whether we had transplanted [on] any HIV-positive patients, and found these two,” says Cooper.
The first patient had received a bone-marrow transplant for non-Hodgkin’s lymphoma in 2011. His replacement stem cells came from a donor who carried one copy of a gene thought to afford protection against the virus. The other had been treated for leukaemia in 2012.
Unfortunately, several months after the ‘Boston’ patients stopped taking ART, the virus returned. An infant born with HIV in Mississippi who received antiretroviral therapy soon after birth, then stopped it for more than three years, was thought to have been cured, but has had the virus rebound, too.
At the moment, there is only one person in the world who is still considered cured of HIV: Timothy Ray Brown, the ‘Berlin patient’, who received a bone-marrow transplant and has had no signs of the virus in his blood for six years without ART. The bone marrow received by the Berlin patient came from a donor who happened to have a natural genetic resistance to his strain of HIV.
“It is very possible that the Australian men would relapse if they were to stop antiretroviral therapy,” says Timothy Henrich, an infectious-disease specialist at Brigham and Women’s Hospital who helped to treat the Boston men.
Because of the risk of relapse, Cooper’s team will not claim that their patients are cured. But, he says, the results show that “there is something about bone-marrow transplantation in people with HIV that has an anti-HIV reservoir effect, such that the reservoirs go down to very low levels. And if we can understand what that is and how that happens, it will really accelerate the field of cure search”.
Stem-cell transplant in itself cannot be used as a routine HIV treatment, because of the high mortality (10%) associated with the procedure. An important next step will be to find more such cases and compare them, says Cooper, to try to identify where the virus might be hiding. “These patients are very precious examples to help us understand how we might manipulate the immune system to drive the reservoir down to these extraordinary low levels.”
Henrich says that a larger pool of patients will provide a better understanding of how the immune system can be harnessed to fight HIV, adding that there could be many more people around the world whose virus has become undetectable.
The fight in preventing the HIV/AIDS virus may be a tough one and it will take a lot of comprehensive studies and research to knock it down but as long as we have researchers, doctors and advocates devoted to put an end to the disease, The cure for HIV/AIDS will be discovered as soon as possible.  

This website and its content is copyright of oddityworld.net
© Oddity World 2015. All rights reserved
You have our permission to reprint this article via creative commons license if you attribute us with a live backlink to this article. - ODDITYWORLD.NET


Related

News 3452283835768773813

Mag-post ng isang Komento

  1. Hello, every one. Am mr roland from UK, I believe is possible that cancer
    can be cure, what a great man he have done it for me, also I never believe
    all this comment and post about him, I was very sick, I am cancer positive
    over 8 year,just last year I keep reading the testimony post about this man
    named Dr,George, they said that the man is so powerful he have cured
    different diseases, I keep monitoring the post of some people about this man
    and I found out this man is real I contacted him for help because I was
    having such problem this man reply to my email after some hours, I inform
    he about my problem that I have this virus for 8 year now this man said
    that I should not worry and I should not disappoint him, what he is about to
    do for me now is just a gift from his gods and his father's, that i should show appreciation to him
    if am cured I should tell people true about him, I said no problem
    because I never have the believe that I will be cured someday but thank
    god for my life for curing me through this man this man ask for my details
    which i send to him, and he said that he want to have some consultation on
    it, he said that I need to provide some items needed for the curing of the cancer,he cured me,i
    I found out there was no cancer found in my body again what a miracle
    thanks doctor George for helping me out from this illness i will continue
    doing this according to my promise if you need his help just contact him
    now through his email aknemutemple@gmail.com or call him on +2348166103674

    TumugonBurahin
  2. I am Canthy Smarth from United Kingdom. I was in trouble when doctor told me that I have been diagnosed with HIV... I though about my children and my husband, I know my children will face a serious problem when I'm gone, I lost hope and I wept all day, but one day I was surfing the internet I found Dr. CUBA's contact number. I called him and he guided me. I asked him for solutions and he started the remedies for my health. Thank God, now everything is fine, I'm cured by Dr. CUBA herbal medicine, I'm very thankful to Dr. CUBA and very happy with my hubby and children. email him on drcubatemple@gmail.com; drcubatemple@gmail.com, call me on +447031986033 , email me on canthysmarth09@gmail.com I am from New York. I was in trouble when doctor told me that I have been diagnosed with HIV... I though about my children and my husband, I know my children will face a serious problem when I'm gone, I lost hope and I wept all day, but one day I was surfing the internet I found Dr. CUBA's contact number. I called him and he guided me. I asked him for solutions and he started the remedies for my health. Thank God, now everything is fine, I'm cured by Dr. CUBA herbal medicine, I'm very thankful to Dr. CUBA and very happy with my hubby and children. email him on drcubatemple@gmail.com; drcubatemple@gmail.com, call him on +2348062477418, email me on canthysmarth09@gmail.com

    TumugonBurahin

emo-but-icon

FOLLOW US ON:

LIKE US ON FACEBOOK

Recent

Hot in week

Comments

POPULAR POSTS

Random Posts

item